One-pot and divergent synthesis of polysubstituted quinolin-2(1<i>H</i>)-ones and oxireno[2,3-<i>c</i>]quinolin-2(1a<i>H</i>,3<i>H</i>,7b<i>H</i>)-ones <i>via</i> sequential Ugi/Knoevenagel condensation/hydrolysis and Ugi/Corey–Chaykovsky epoxidation reactions
Mao-Lin Yang, Hong‐Ling Pan, Han‐Han Kong, Ming‐Wu Ding
Abstract
A new one-pot and divergent synthesis of multisubstituted quinolin-2(1 H )-ones and oxireno[2,3- c ]quinolin-2(1a H ,3 H ,7b H )-ones was developed.
Topics & Concepts
ChemistryDivergent synthesisStereochemistryCombinatorial chemistryOrganic chemistryCatalysisMulticomponent Synthesis of HeterocyclesSynthesis of Organic CompoundsSynthesis and biological activity