Reductive umpolung for asymmetric synthesis of chiral α-allenic alcohols
Yui Kondo, Kazunori Nagao, Hirohisa Ohmiya
Abstract
Copper-catalyzed reductive umpolung provides a new synthetic route to chiral α-allenic alcohols.
Topics & Concepts
UmpolungChemistryCombinatorial chemistryEnantioselective synthesisOrganic chemistryCatalysisNucleophileAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and CatalysisSynthetic Organic Chemistry Methods