Dendrobium nobile Lindl. alkaloid decreases Tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β pathway in vitro and in vivo
Juan Huang, Nanqu Huang, Yu Qiu, Jingshan Shi
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BGSK-3HyperphosphorylationGSK3BGlycogen synthaseWortmanninPharmacologyChemistryKinaseBiologySignal transductionBiochemistryPhosphorylationBiological and pharmacological studies of plantsBioactive Compounds in PlantsNatural Compound Pharmacology Studies