A novel 8-nitro quinoline-thiosemicarbazone analogues induces G1/S & G2/M phase cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway

Selvaraj Shyamsivappan, Raju Vivek, Arjunan Saravanan, Thangaraj Arasakumar, T. Suresh, S. Athimoolam, P. S. Mohan

2020Bioorganic Chemistry26 citationsDOI

Topics & Concepts

ChemistryApoptosisQuinolineCell cycle checkpointCell cycleProgrammed cell deathMTT assayCell growthBiochemistryOrganic chemistrySynthesis and biological activityMetal complexes synthesis and propertiesCancer therapeutics and mechanisms

A novel 8-nitro quinoline-thiosemicarbazone analogues induces G1/S &amp; G2/M phase cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway

Topics & Concepts

A novel 8-nitro quinoline-thiosemicarbazone analogues induces G1/S & G2/M phase cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway