Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers
Misato Ota, Yasuhito Maki, Lingyu Xu, Toshiaki Makino
Topics & Concepts
PentobarbitalCaffeinePharmacologyPharmacokineticsFlumazenilHypnoticSedativeMedicineOrexinChemistryGABAergicGABAA receptorReceptorEndocrinologyInternal medicineNeuropeptideMedicinal Plant Extracts EffectsSleep and related disordersAlkaloids: synthesis and pharmacology