Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents
Chuanbiao Du, Xinlong Yang, Yan Long, Xueqing Lang, Lige Liu, Yajie Xu, Hu Wu, Yiwen Chu, Xiaolei Hu, Junfeng Deng, Qinggang Ji
Topics & Concepts
ChemistryChitin synthaseAntifungalQuinazolinoneChitinIC50StereochemistryEnzymeFluconazoleIn vitroBiochemistryMicrobiologyChitosanBiologyQuinazolinone synthesis and applicationsPlant-Microbe Interactions and ImmunityFungal Plant Pathogen Control