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Guard cells on the adaxial and abaxial leaf surfaces use different compositions of potassium ion channels to drive light-induced stomatal opening

Jian Wei, K. Hu, Menglong Liu, Yali Liu, Wang Tian, Yue Zhou, Liu-Min Fan, Yizhou Wang, Yin Wang

2025Nature Plants19 citationsDOIOpen Access PDF

Abstract

In the leaves of most herbaceous plants, stomata exist in both the adaxial (upper) and abaxial (lower) surfaces1,2. Many previous studies have reported that stomata on the abaxial surface are more responsive to light than those on the adaxial surface3–9. However, the underlying molecular mechanism is still unclear. Here, by examining the model plants Arabidopsis and tobacco, we confirmed that the distinct feature occurred at the guard cell level. Next, with both single-cell RNA sequencing and transcriptome sequencing, we compared gene expression patterns of adaxial and abaxial guard cells and highlighted the possibility of different utilization of potassium ion (K+) channels. Via in silico OnGuard simulation and genetic modifications, we found that adaxial and abaxial guard cells rely on different K+in channels, which control K+ influx for stomatal opening. The present study provides insights into understanding the distinct stomatal light response of different leaf surfaces. This study combines single-cell RNA sequencing, in silico OnGuard simulation and genetic modification approaches to reveal distinct compositional differences in the potassium ion channel between adaxial and abaxial guard cells.

Topics & Concepts

Guard cellPotassiumGuard (computer science)BiophysicsBotanyChemistryIon channelPotassium channelEnvironmental scienceBiologyComputer scienceBiochemistryReceptorProgramming languageOrganic chemistryPlant Molecular Biology ResearchLight effects on plantsPlant and Biological Electrophysiology Studies
Guard cells on the adaxial and abaxial leaf surfaces use different compositions of potassium ion channels to drive light-induced stomatal opening | Litcius