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Positronium imaging with the novel multiphoton PET scanner

P. Moskal, K. Dulski, N. Chug, C. Curceanu, E. Czerwiński, M. Dadgar, J. Gajewski, A. Gajos, Grzegorz Grudzień, Beatrix C. Hiesmayr, K. Kacprzak, Ł. Kapłon, Hanieh Karimi, K. Klimaszewski, G. Korcyl, P. Kowalski, T. Kozik, N. Krawczyk, W. Krzemień, E. Kubicz, Piotr Małczak, Szymon Niedźwiecki, M. Pawlik-Niedźwiecka, Michał Pędziwiatr, L. Raczyński, Juhi Raj, Antoni Ruciński, S. Sharma, Shivani Shivani, R. Y. Shopa, M. Silarski, M. Skurzok, Ewa Stępień, Monika Szczepanek, F. Tayefi, W. Wiślicki

2021Science Advances181 citationsDOIOpen Access PDF

Abstract

; therefore, positronium imaging may provide information about disease progression during the initial stages of molecular alterations. Current PET systems do not allow acquisition of positronium images. This study presents a new method that enables positronium imaging by simultaneous registration of annihilation photons and deexcitation photons from pharmaceuticals labeled with radionuclides. The first positronium imaging of a phantom built from cardiac myxoma and adipose tissue is demonstrated. It is anticipated that positronium imaging will substantially enhance the specificity of PET diagnostics.

Topics & Concepts

PositroniumScannerPet imagingPositron emission tomographyComputer scienceNuclear medicineOpticsComputer visionMedical physicsPhysicsArtificial intelligenceMedicinePositronNuclear physicsElectronMuon and positron interactions and applicationsMedical Imaging Techniques and ApplicationsAtomic and Subatomic Physics Research
Positronium imaging with the novel multiphoton PET scanner | Litcius