Minisci-Type Dehydrogenative Coupling of N-Heteroaromatic Rings with Inert C(sp<sup>3</sup>)–H Enabled by a Visible-Light-Catalyzed Intermolecular Hydrogen Atom Transfer Process
Junfeng Yang, Yunfei Liu, Linlin Wei, Kai-Kai Qiao, Yanqiu Zhao, Lei Shi
Abstract
The Minisci-type dehydrogenative coupling of N-heteroaromatic rings with inert C-H or Si-H partners via visible-light-catalyzed hydrogen atom transfer has been reported. This methodology allows the coupling reactions to be carried out in water as a solvent under air atmospheric conditions with visible-light illumination. A wide range of inert C-H and Si-H partners could be directly coupled with various N-aromatic heterocycles to deliver products in good to excellent yields.
Topics & Concepts
ChemistryIntermolecular forceInertCatalysisPhotochemistryHydrogen atomSolventHydrogenVisible spectrumAtom (system on chip)Coupling (piping)MoleculeOrganic chemistryOptoelectronicsMechanical engineeringEngineeringComputer sciencePhysicsEmbedded systemAlkylRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques