Asymmetric difluorocarbonylation reactions of non-active imines catalyzed by Bi(OAc)<sub>3</sub>/chiral phosphoric acid
Yuliang Pan, Yingbo Shao, Zhen Liu, Hanliang Zheng, Liu Cai, Hai-Chang Zhang, Xin Li
Abstract
Difluorinated carbonyl has been identified as the basic skeleton of multitudinous biologically active molecules.
Topics & Concepts
ChemistryPhosphoric acidCatalysisOptically activeMoleculeCombinatorial chemistryOrganic chemistryMedicinal chemistryFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsAsymmetric Synthesis and Catalysis