Multiple medicinal chemistry strategies of targeting KRAS: State-of-the art and future directions
Yanguo Shang, Shengnan Fu, Qingjing Hao, Hanjie Ying, Jinxin Wang, Tao Shen
Topics & Concepts
KRASDrug discoveryChemistryCancer researchCancerColorectal cancerComputational biologyPharmacologyMedicineBiologyInternal medicineBiochemistryProtein Kinase Regulation and GTPase SignalingBiochemical and Molecular ResearchEnzyme Structure and Function