LncRNA MEG3 suppresses PI3K/AKT/mTOR signalling pathway to enhance autophagy and inhibit inflammation in TNF-α-treated keratinocytes and psoriatic mice
Zhanli Tang, Kai Zhang, Shao-Cong Lv, Gui-Wen Xu, Jianfen Zhang, Haiyan Jia
Topics & Concepts
HaCaTPI3K/AKT/mTOR pathwayProtein kinase BImiquimodPsoriasisCancer researchChemistryTumor necrosis factor alphaMolecular biologyBiologySignal transductionImmunologyCell biologyIn vitroBiochemistryPsoriasis: Treatment and PathogenesisCancer-related molecular mechanisms researchInflammasome and immune disorders