EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier
Jian Fang, Zhuangwei Zhang, Yinyin Cheng, Haitao Yang, Hui Zhang, Zhe Xue, Songtao Lu, Yichen Dong, Chunyan Song, Xiaohong Zhang, Yuping Zhou
Abstract
: EPA and DHA differentially coordinate the interaction between the host and the gut microbiota and relieve mucus barrier disruption in DSS-induced colitis. EPA may develop into a promising adjunctive therapy for UC.
Topics & Concepts
MucusMucinColitisGut floraInflammatory bowel diseaseBiologyMicrobiologyMicrobiomeCecumDocosahexaenoic acidEicosapentaenoic acidImmunologyBiochemistryFatty acidInternal medicinePolyunsaturated fatty acidMedicineBioinformaticsDiseaseEcologyHelicobacter pylori-related gastroenterology studiesGut microbiota and healthProbiotics and Fermented Foods