Litcius/Paper detail

Updating the portfolio of physicochemical descriptors related to permeability in the beyond the rule of 5 chemical space

Giuseppe Ermondi, Maura Vallaro, Gilles H. Goetz, Marina Shalaeva, Giulia Caron

2020European Journal of Pharmaceutical Sciences56 citationsDOI

Topics & Concepts

LipophilicityMolecular descriptorChemistryChemical spaceDrug discoveryPartition coefficientPolarity (international relations)Biological systemQuantitative structure–activity relationshipChromatographyOrganic chemistryStereochemistryBiochemistryCellBiologyComputational Drug Discovery MethodsChemical Synthesis and AnalysisReceptor Mechanisms and Signaling
Updating the portfolio of physicochemical descriptors related to permeability in the beyond the rule of 5 chemical space | Litcius