ALPK1 signaling pathway activation by HMGB1 drives microglial pyroptosis and ferroptosis and brain injury after acute ischemic stroke
Ou Du, Yu Yan, Ya-Ling Yan, Yuxin Yang, Anguo Wu, An-Guo Wu, Kuan Li, Gan Qiao, Junrong Du, Fangyi Long, Fangyi Long
Topics & Concepts
PyroptosisHMGB1Stroke (engine)MedicineSignal transductionMicrogliaNeuroscienceImmunologyCell biologyInflammationBiologyInflammasomeEngineeringMechanical engineeringAdvanced Glycation End Products researchInflammasome and immune disordersFerroptosis and cancer prognosis