Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides
Christina L. Koumpoura, Michel Nguyen, Christian Bijani, Laure Vendier, Elena G. Salina, Silvia Buroni, Giulia Degiacomi, Sandrine Cojean, Philippe M. Loiseau, Françoise Benoit‐Vical, Alfonso T. García‐Sosa, Anne Robert, Michel Baltas
Abstract
showed the most favorable interactions.
Topics & Concepts
LawsoneChemistryPlasmodium falciparumLeishmania donovaniJugloneStereochemistryMycobacterium tuberculosisPotencyIC50Combinatorial chemistryOrganic chemistryBiologyBiochemistryTuberculosisIn vitroLeishmaniasisMedicineMalariaPathologyVisceral leishmaniasisImmunologyBioactive Compounds and Antitumor AgentsMulticomponent Synthesis of HeterocyclesSynthesis and Biological Evaluation