A bifunctional molecular catalyst built up of <scp>l</scp>-proline grafted polyoxometalate for one-pot three-component green synthesis of heterocycles
Guoyong Dai, Qi Li, Dejin Zang, Yongge Wei
Abstract
This work demonstrates the potential of covalent combination of polyoxometalate and organocatalyst in tandem synthesis, enabling a one-pot alcohol oxidation/three-component continuous catalytic reaction for synthesizing pharmacological heterocyclic compounds in high yields.
Topics & Concepts
PolyoxometalateBifunctionalCatalysisChemistryTandemOrganocatalysisCovalent bondComponent (thermodynamics)Combinatorial chemistryAlcoholOrganic chemistryEnantioselective synthesisMaterials scienceComposite materialThermodynamicsPhysicsChemical Synthesis and ReactionsPolyoxometalates: Synthesis and ApplicationsOxidative Organic Chemistry Reactions