GuRhaGT, a highly specific saponin 2′′-<i>O</i>-rhamnosyltransferase from<i>Glycyrrhiza uralensis</i>
Zilong Wang, Jia-Jing Zhou, Bo-Yun Han, Aobulikasimu Hasan, Ya-Qun Zhang, Jia-He Zhang, Haidong Wang, Bin Li, Xue Qiao, Min Ye
Abstract
GuRhaGT is the first saponin 2′′- O -rhamnosyltransferase with broad substrate promiscuity, high sugar donor- and regio-specificity. It could be an efficient biocatalyst for the synthesis of bioactive saponins.
Topics & Concepts
Glycyrrhiza uralensisSaponinChemistryGlycyrrhizaDammaraneTraditional medicineStereochemistryTriterpeneMedicineAlternative medicinePathologyPharmacological Effects of Natural CompoundsNatural product bioactivities and synthesisGinseng Biological Effects and Applications