Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings
Yuchen Fan, Diamanda Rigas, Lee Joon Kim, Feng-Peng Chang, Nanzhi Zang, K C McKee, C. Kemball, Zhixin Yu, P. Winkler, Wan-Chih Su, Pierce Jessen, Greg L. Hura, Tao Chen, Stefan G. Koenig, Karthik Nagapudi, Dennis Leung, Chun‐Wan Yen
Topics & Concepts
ChemistryMessenger RNAFreeze-dryingPeripheral blood mononuclear cellSmall-angle X-ray scatteringBiochemistryChromatographyIn vitroPhysicsGeneOpticsScatteringViral gastroenteritis research and epidemiologyRNA Interference and Gene DeliveryVirus-based gene therapy research