Celastrol, which targets IL-2/CD25 binding inhibition, induces T cell-mediated antitumor activity in melanoma
Okki Cho, Joong-Woon Lee, Youngjin Jeong, Lee Kyung Kim, Bokyung Jung, Tae‐Hwe Heo
Topics & Concepts
IL-2 receptorFOXP3Cancer researchCD8T cellImmune systemMelanomaPharmacologyImmunotherapyCell growthInterleukin 2ChemistryBiologyImmunologyBiochemistryNatural Compounds in Disease TreatmentImmunotherapy and Immune ResponsesCell Adhesion Molecules Research