TNX-1500, a crystallizable fragment–modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival
Grace Lassiter, Ryo Otsuka, Takayuki Hirose, Ivy A. Rosales, Ahmad Karadagi, Toshihide Tomosugi, A. Dehnadi, Hang Lee, Robert B. Colvin, Jason Baardsnes, Anna N. Moraitis, Emma E. Smith, Zahida Ali, Phil Berhe, Andrew Mulder, Bernd Meibohm, Bruce Daugherty, Siobhan Fogarty, Richard N. Pierson, Seth Lederman, Tatsuo Kawai
Topics & Concepts
CD154Monoclonal antibodyMedicineAntibodyIn vivoKidneyImmunologyBlockadeIn vitroKidney transplantationReceptorPlatelet activationPlateletCD40BiologyInternal medicineBiochemistryCytotoxic T cellBiotechnologyComplement system in diseasesRenal Transplantation Outcomes and TreatmentsT-cell and B-cell Immunology