Litcius/Paper detail

Downregulation of DDIT4 ameliorates abnormal behaviors in autism by inhibiting ferroptosis via the PI3K/Akt pathway

Ting Luo, Sisi Chen, Ye Ruan, Huaying Chen, Yumei Chen, Yamin Li, Wen Zhou

2022Biochemical and Biophysical Research Communications22 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayDownregulation and upregulationProtein kinase BGene knockdownGPX4ChemistryCell biologyCancer researchBiologySignal transductionOxidative stressApoptosisBiochemistrySuperoxide dismutaseGeneGlutathione peroxidaseEpigenetics and DNA MethylationGenetics and Neurodevelopmental DisordersMicroRNA in disease regulation