Photodynamic Hydrogen-Bonded Biohybrid Framework: A Photobiocatalytic Cascade Nanoreactor for Accelerating Diabetic Wound Therapy
Wei Huang, Haitao Yuan, Huangsheng Yang, Linjing Tong, Rui Gao, Xiaoxue Kou, Jigang Wang, Xiaomin Ma, Siming Huang, Fang Zhu, Guosheng Chen, Gangfeng Ouyang
Abstract
into toxic reactive oxygen species by the photobiocatalytic cascade. As a result, it readily reverses the microenvironment of the diabetes wound and exhibits an extraordinary capacity for wound healing through synergistic photodynamic therapy. This work describes the first example of constructing an all-in-one HOF bioreactor for antimicrobial diabetes wound treatment and showcases the promise of combined biocatalysis and photocatalysis achieved by using an HOF scaffold in biomedicine applications.
Topics & Concepts
NanoreactorPhotodynamic therapyScaffoldWound healingCascadeNanotechnologyChemistryMaterials scienceMedicineBiomedical engineeringSurgeryOrganic chemistryChromatographyNanoparticleNanoplatforms for cancer theranosticsAntimicrobial agents and applicationsWound Healing and Treatments