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Case Report: Tropheryma whipplei Hide in an AIDS Patient With Pneumocystis Pneumonia

Jun Yan, Binhai Zhang, Zhongdong Zhang, Jinchuan Shi, Shourong Liu, Jianjiang Qi, Mengyan Wang

2021Frontiers in Public Health17 citationsDOIOpen Access PDF

Abstract

Introduction: Pneumocystis pneumonia (PCP) is one of the most common opportunistic infections in HIV-infected patients. However, coinfection with Tropheryma whipplei is infrequent in AIDS patients with PCP. Case Presentation: We report a 28-year-old male AIDS patient coinfected with T. whipplei and Pneumocystis jirovecii diagnosed in the bronchoalveolar lavage. After sulfamethoxazole–trimethoprim and meropenem treatment, the patient showed clinical improvement in 2 weeks. Conclusion: Clinicians need to be alert to the occurrence of T. whipplei infection in AIDS patients with PCP and timely diagnosis and antibacterial treatments are essential. This case may help clinicians for timely diagnosis of the coinfection of T. whipplei and P. jirovecii in AIDS patients.

Topics & Concepts

Tropheryma whippleiCoinfectionPneumocystis jiroveciiMedicinePneumocystis cariniiPneumoniaBronchoalveolar lavagePneumocystis pneumoniaOpportunistic infectionImmunologySulfamethoxazoleTrimethoprimIntensive care medicineInternal medicineHuman immunodeficiency virus (HIV)DiseaseMicrobiologyAntibioticsWhipple's diseaseViral diseaseBiologyLungWhipple's Disease and Interleukins