Litcius/Paper detail

COVID-19 IgG-related autoimmune inflammatory necrotizing myositis

Maedeh Veyseh, Sai Koyoda, Bibi Ayesha

2021BMJ Case Reports23 citationsDOIOpen Access PDF

Abstract

The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected millions of people around the globe. The most common presentation of COVID-19 is fever and upper and lower respiratory tract infection. Myalgia is fairly common in the prodromal phase of the viral illness which self-resolves. There is very scant literature on autoimmune myositis triggered by COVID-19 infection. We report a case of SARS-CoV-2 infection, who presented with progressive muscle weakness with rhabdomyolysis and necrotizing autoimmune myopathy on muscle biopsy. This case report imposes awareness of musculoskeletal autoimmune processes triggered by COVID-19 which requires clinical suspicion for early diagnosis and initiation of treatment.

Topics & Concepts

myalgiaMedicineMyositisRhabdomyolysisCoronavirus disease 2019 (COVID-19)ImmunologyMuscle biopsyPandemicBiopsyPathologyDiseaseInternal medicineInfectious disease (medical specialty)Muscle and Compartmental DisordersInflammatory Myopathies and DermatomyositisLong-Term Effects of COVID-19