Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease
Haiyong Liang, Peipei Zhang, Xile Zhang, Yanyan Zheng, Yanran Huang, Guo‐qing Zheng, Yan Lin
Abstract
< 0.05), but there were no significant effects in animals with neuronal degeneration induced by chronic stress or in SAMP8 transgenic mice. The potential mechanisms included antioxidant and anti-inflammatory effects, amelioration of Alzheimer's disease-related pathology, synapse protection, and up-regulation of nerve cells via multiple signaling pathways.
Topics & Concepts
Cognitive impairmentMedicineDiseaseGinsenosideGinsenoside Rg1PharmacologyNeurosciencePsychologyInternal medicinePathologyAlternative medicineGinsengGinseng Biological Effects and ApplicationsPharmacological Effects of Natural CompoundsMedicinal Plants and Bioactive Compounds