Bioactive PCL microspheres with enhanced biocompatibility and collagen production for functional hyaluronic acid dermal fillers
Yun Heo, Sangwoo Shin, Da‐Seul Kim, Semi Lee, Soyeun Park, Seung‐Woon Baek, Jun‐Kyu Lee, Jun Hyuk Kim, Dong Keun Han
Abstract
Polymeric microspheres containing magnesium hydroxide (MH) and a bioactive agent (BA), such as apocynin (APO) and astaxanthin (ATX), have been prepared as functional dermal fillers with enhanced physicochemical and biological performance.
Topics & Concepts
Hyaluronic acidBiocompatibilityChemistryMicrospherePolycaprolactoneIn vivoWound healingNuclear chemistryBiomedical engineeringChemical engineeringPolymerSurgeryOrganic chemistryAnatomyBiotechnologyEngineeringBiologyMedicineWound Healing and TreatmentsDermatologic Treatments and ResearchFacial Rejuvenation and Surgery Techniques