Sensitive HPLC-DMS/MS/MS method coupled with dispersive magnetic solid phase extraction followed by in situ derivatization for the simultaneous determination of multiplexing androgens and 17-hydroxyprogesterone in human serum and its application to patients with polycystic ovarian syndrome
Xianhua Zhang, Huiyu Xu, Guoshuang Feng, Li Yang, Libo Zhao, Rong Li, Rongsheng Zhao
Topics & Concepts
DerivatizationChromatographyAnalyteChemistrySolid phase extractionMass spectrometryLiquid chromatography–mass spectrometryHigh-performance liquid chromatographyExtraction (chemistry)ReagentPhysical chemistryHormonal and reproductive studiesOvarian function and disordersElectrochemical sensors and biosensors