Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models
Steven N. Seyedin, M.M. Hasibuzzaman, Vivan Pham, Michael S. Petronek, Cameron M. Callaghan, Amanda L. Kalen, Kranti A. Mapuskar, Sarah L. Mott, Douglas R. Spitz, Bryan G. Allen, Joseph M. Caster
Topics & Concepts
VeliparibPARP inhibitorCancer researchRadiosensitizerMedicineProinflammatory cytokineRadiation therapyImmune systemColorectal cancerCombination therapyCancerPharmacologyPoly ADP ribose polymeraseImmunologyBiologyInternal medicineInflammationGenePolymeraseBiochemistryCancer Immunotherapy and BiomarkersPARP inhibition in cancer therapyEffects of Radiation Exposure