Gut Microbiota in Liver Disease: What Do We Know and What Do We Not Know?
Lu Jiang, Bernd Schnabl
Abstract
The gut and the liver have a bidirectional communication via the biliary system and the portal vein. The intestinal microbiota and microbial products play an important role for modulating liver diseases such as alcohol-associated liver disease, non-alcoholic fatty liver disease and steatohepatitis, and cholestatic liver diseases. Here, we review the role of the gut microbiota and its products for the pathogenesis and therapy of chronic liver diseases.
Topics & Concepts
Fatty liverSteatohepatitisGut floraLiver diseaseDiseasePathogenesisMedicineChronic liver diseaseGastroenterologyBiologyImmunologyInternal medicineCirrhosisLiver Disease Diagnosis and TreatmentGut microbiota and healthPancreatitis Pathology and Treatment