New agents for DOAC reversal: a practical management review
Katie M White, Uzma Faruqi, Alexander Cohen
Abstract
Bleeding is the commonest and most concerning adverse event associated with anticoagulants. Bleeding, depending on the severity, is managed in various ways, and for severe or life-threatening bleeding, specific antidotes are indicated and recommended. This review provides guidance relating to specific direct oral anticoagulant (DOAC) reversal agents, the antidotes. We discuss their indications for use, dosing, and potential side effects.
Topics & Concepts
MedicineDosingIntensive care medicineAdverse effectMajor bleedingPharmacologyAtrial fibrillationInternal medicineAtrial Fibrillation Management and OutcomesVenous Thromboembolism Diagnosis and ManagementAntiplatelet Therapy and Cardiovascular Diseases