Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1
Gaku Oguri, Toshiaki Nakajima, Hironobu Kikuchi, Shotaro Obi, Fumitaka Nakamura, Issei Komuro
Abstract
-permeable nonselective cation currents induced by AITC, possibly via TRPA1 in human cardiac fibroblast.
Topics & Concepts
Allyl isothiocyanateChemistryPatch clampBiophysicsIntracellularEGTAExtracellularAgonistChannel blockerIon channelPipetteFluorescein isothiocyanateRuthenium redBiochemistryReceptorCalciumBiologyOrganic chemistryQuantum mechanicsFluorescencePhysicsPhysical chemistryIon Channels and ReceptorsPostharvest Quality and Shelf Life ManagementPlant Stress Responses and Tolerance