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Spectrum of Diabetic Neuropathy: New Insights in Diagnosis and Treatment

Brendan R. Dillon, Lynn Ang, Rodica Pop‐Busui

2024Annual Review of Medicine62 citationsDOIOpen Access PDF

Abstract

Diabetic neuropathy is a highly prevalent complication of diabetes. It consists of a broad range of neuropathic conditions, such as distal symmetric polyneuropathy and various forms of autonomic neuropathies involving the cardiovascular, gastrointestinal, and urogenital systems. Prevention or diagnosis in early stages of disease is crucial to prevent symptomatic onset and progression, particularly in the absence of current disease-modifying therapies. In this review, we describe the four main types of diabetic neuropathy. We review current understanding with respect to diagnosis and treatment while highlighting knowledge gaps and future directions.

Topics & Concepts

MedicineDiabetic neuropathyDiabetes mellitusIntensive care medicineDiseaseComplicationAutonomic neuropathyPolyneuropathyGenitourinary systemDermatologySurgeryInternal medicineEndocrinologyCell cultureGeneticsNeuroblastomaBiologyPain Mechanisms and TreatmentsBotulinum Toxin and Related Neurological DisordersPharmacology and Obesity Treatment
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