Deficiency of protein inhibitor of activated STAT3 exacerbates atherosclerosis by modulating VSMC phenotypic switching
Haole Liu, Jingyi Zhang, Ziyang Xue, Mingke Chang, Xinxin Feng, Yifan Cai, Liang Bai, Weirong Wang, Enqi Liu, Sihai Zhao, Rong Wang
Topics & Concepts
SUMO proteinVimentinVascular smooth muscleImmunoprecipitationPhenotypePhenotypic switchingCancer researchUbiquitin ligaseDownregulation and upregulationCell biologyBiologyUbiquitinMolecular biologyChemistryCell cultureImmunologyEndocrinologyBiochemistryImmunohistochemistryGeneGeneticsSmooth muscleCytokine Signaling Pathways and Interactionsinterferon and immune responsesProtein Tyrosine Phosphatases