Photoswitchable gRNAs for Spatiotemporally Controlled CRISPR-Cas-Based Genomic Regulation
Elena Moroz, Dwiantari Satyapertiwi, Marie‐Christine Ramel, Håkon Høgset, Ilona Sunyovszki, Ziqian Liu, Jonathan P. Wojciechowski, Yueyun Zhang, Christopher L. Grigsby, Liliana Brito, Laurence Bugeon, Margaret J. Dallman, Molly M. Stevens
Abstract
, enabling the use of this strategy for developmental biology and tissue engineering applications.
Topics & Concepts
CRISPRGenome editingGuide RNAComputational biologyTrans-activating crRNASynthetic biologyBiologyGeneRNAGeneticsCRISPR and Genetic EngineeringPhotochromic and Fluorescence ChemistryRNA Interference and Gene Delivery