CGI1746 targets σ1R to modulate ferroptosis through mitochondria-associated membranes
Zili Zhang, Hong Zhou, Wenjia Gu, Yuehan Wei, Shan Mou, Youjun Wang, Jing Zhang, Qing Zhong
Topics & Concepts
Cell biologyProgrammed cell deathIron homeostasisHomeostasisMitochondrionPolyunsaturated fatty acidChemistryKinaseCellOxidative phosphorylationReactive oxygen speciesBiochemistryBiologyFatty acidApoptosisMetabolismFerroptosis and cancer prognosisCancer Mechanisms and TherapyDrug Transport and Resistance Mechanisms