Red raspberry (<i>Rubus idaeus</i>) preserves intestinal barrier integrity and reduces oxidative stress in Caco-2 cells exposed to a proinflammatory stimulus
Mirko Marino, Marco Rendine, Samuele Venturi, Marisa Porrini, Claudio Gardana, Dorothy Klimis‐Zacas, Patrizia Riso, Cristian Del Bo’
Abstract
Red raspberry enhanced intestinal barrier integrity, as evidenced by increased TEER and decreased FITC-D permeability. Further, red raspberry positively modulated the tight junction protein claudin-1 and reduced oxidative stress biomarkers 8-OHdG.
Topics & Concepts
Oxidative stressBlowing a raspberryTight junctionProinflammatory cytokineOccludinCaco-2ChemistryIntestinal permeabilityRubusCell biologyBiologyImmunologyFood scienceBiochemistryInflammationBotanyIn vitroBarrier Structure and Function StudiesNeurological Disease Mechanisms and TreatmentsConnexins and lens biology