A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype
Martina Hýžďalová, Jiřina Procházková, Simona Strapáčová, Lucie Svržková, Ondřej Vacek, Radek Fedr, Zdeněk Andrysík, Eva Hrubá, Helena Líbalová, Jǐŕı Kléma, Jan Topinka, Josef Mašek, Karel Souček, Jan Vondráček, Miroslav Machala
Topics & Concepts
Epithelial–mesenchymal transitionA549 cellAryl hydrocarbon receptorCell growthCancer researchCarcinogenesisCell cycleSenescenceCellBiologyChemistryCell biologyCancerMetastasisGeneTranscription factorBiochemistryGeneticsCancer-related Molecular PathwaysCancer Cells and MetastasisEpigenetics and DNA Methylation