Novel benzothiazole hybrids targeting EGFR: Design, synthesis, biological evaluation and molecular docking studies
Eman A. Abd El‐Meguid, Gaber O. Moustafa, Hanem M. Awad, Eman R. Zaki, Eman S. Nossier
Topics & Concepts
ChemistryBenzothiazoleErlotinibDocking (animal)ThiazoleIC50PotencyCell cycle checkpointEGFR inhibitorsIn vitroPharmacologyCell cycleApoptosisCell culturePharmacophoreEpidermal growth factor receptorBiochemistryStereochemistryReceptorMedicineNursingGeneticsBiologySynthesis and biological activityComputational Drug Discovery MethodsLung Cancer Treatments and Mutations