Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors
Guangcheng Wang, Wenjing Liu, Juan Tang, Xue Ma, Zipeng Gong, Yong Huang, Yongjun Li, Zhiyun Peng
Topics & Concepts
ChemistryMoietyCytotoxicityStereochemistryTubulinDocking (animal)BenzophenoneCisplatinCombinatorial chemistryIn vitroMicrotubuleBiochemistryOrganic chemistryCell biologyMedicineBiologyNursingSurgeryChemotherapySynthesis and biological activityClick Chemistry and ApplicationsFungal Plant Pathogen Control