Multiple isogenic GNE-myopathy modeling with mutation specific phenotypes from human pluripotent stem cells by base editors
Ju-Chan Park, Jumee Kim, Hyeon‐Ki Jang, Seungyeon Lee, Keun-Tae Kim, Eun‐Ji Kwon, Seokwoo Park, Hyun Sik Lee, Hyewon Choi, Seung‐Yeol Park, Hee‐Jung Choi, Soon‐Jung Park, Sung‐Hwan Moon, Sangsu Bae, Hyuk‐Jin Cha
Topics & Concepts
Induced pluripotent stem cellPhenotypeBiologyMutationMyopathyGeneGeneticsPoint mutationComputational biologyBioinformaticsEmbryonic stem cellCRISPR and Genetic EngineeringCardiomyopathy and Myosin StudiesPluripotent Stem Cells Research