Photoacoustic computed tomography for functional human brain imaging [Invited]
Shuai Na, Lihong V. Wang
Abstract
The successes of magnetic resonance imaging and modern optical imaging of human brain function have stimulated the development of complementary modalities that offer molecular specificity, fine spatiotemporal resolution, and sufficient penetration simultaneously. By virtue of its rich optical contrast, acoustic resolution, and imaging depth far beyond the optical transport mean free path (∼1 mm in biological tissues), photoacoustic computed tomography (PACT) offers a promising complementary modality. In this article, PACT for functional human brain imaging is reviewed in its hardware, reconstruction algorithms, in vivo demonstration, and potential roadmap.
Topics & Concepts
Diffuse optical imagingMagnetic resonance imagingPreclinical imagingPhotoacoustic imaging in biomedicinePhotoacoustic tomographyMolecular imagingFunctional imagingNeuroimagingOptical imagingModality (human–computer interaction)TomographyComputer scienceFunctional magnetic resonance imagingOptical tomographyHuman brainImage resolutionBiomedical engineeringOpticsMedicineArtificial intelligenceIn vivoPhysicsRadiologyPsychiatryBiotechnologyBiologyPhotoacoustic and Ultrasonic ImagingOptical Imaging and Spectroscopy TechniquesThermography and Photoacoustic Techniques