Design and economic investigation of a Multicolumn Countercurrent Solvent Gradient Purification unit for the separation of an industrially relevant PEGylated protein
Tae Keun Kim, Benedetta Sechi, Juan Jose Romero Conde, James Angelo, Xuankuo Xu, Sanchayita Ghose, Massimo Morbidelli, Mattia Sponchioni
Topics & Concepts
ChemistryChromatographyElutionYield (engineering)Countercurrent exchangeProcess engineeringSimulated moving bedProcess (computing)Polyethylene glycolPetrochemicalSolventDownstream processingAdsorptionComputer scienceOrganic chemistryMaterials scienceThermodynamicsOperating systemEngineeringMetallurgyPhysicsProtein purification and stabilityViral Infectious Diseases and Gene Expression in InsectsInnovative Microfluidic and Catalytic Techniques Innovation