Seneca Valley Virus 3C <sup>pro</sup> Mediates Cleavage and Redistribution of Nucleolin To Facilitate Viral Replication
Jiangwei Song, Rong Quan, Dan Wang, Jue Liu
Abstract
The nucleolus is a subnuclear cellular compartment, and nucleolin (NCL) resides predominantly in the nucleolus. NCL participates in viral replication, translation, internalization, and also serves as a receptor for virus entry.
Topics & Concepts
NucleolinViral replicationNucleolusBiologyCell biologyCleavage (geology)NS2-3 proteaseVirologyVirusCytoplasmPaleontologyFracture (geology)Animal Disease Management and EpidemiologyViral Infections and Immunology ResearchVector-Borne Animal Diseases