LncRNA ARFRP1 knockdown inhibits LPS-induced the injury of chondrocytes by regulation of NF-κB pathway through modulating miR-15a-5p/TLR4 axis.
Guangcheng Zhang, Qing Zhang, Juan Zhu, Jiazhu Tang, Mingjun Nie
Topics & Concepts
Gene knockdownLuciferaseViability assayTLR4ChemistrymicroRNAFlow cytometryMolecular biologyNF-κBApoptosisWestern blotReporter geneTumor necrosis factor alphaCell biologySignal transductionCancer researchTransfectionGene expressionBiologyImmunologyGeneBiochemistryOsteoarthritis Treatment and MechanismsCancer-related molecular mechanisms researchRheumatoid Arthritis Research and Therapies