Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes
K. Tsuchiya, Shoko Hosojima, Hideki Hara, Hiroko Kushiyama, Mamunur Rashid Mahib, Takeshi Kinoshita, Takashi Suda
Abstract
influx, resulting in the calpain-dependent maturation of IL-1α.
Topics & Concepts
InflammasomePyroptosisCell biologyCalpainCaspase 1ChemistryCytokineExtracellularSecretionBiologyBiochemistryImmunologyReceptorEnzymeInflammasome and immune disorders