Fluoroquinolones tackling antimicrobial resistance: Rational design, mechanistic insights and comparative analysis of norfloxacin vs ciprofloxacin derivatives
Aanchal Khanna, Nitish Kumar, Rupali Rana, Jyoti Jyoti, Anchal Sharma, Muskan Muskan, Harmandeep Kaur, Preet Mohinder Singh Bedi
Topics & Concepts
AntimicrobialDNA gyraseNorfloxacinRational designAntibiotic resistanceCiprofloxacinComputational biologyFlexibility (engineering)ChemistryCombinatorial chemistryBiochemical engineeringBiologyAntibioticsMicrobiologyEngineeringEscherichia coliBiochemistryGeneticsMathematicsGeneStatisticsAntibiotics Pharmacokinetics and EfficacyCancer therapeutics and mechanismsAntibiotic Resistance in Bacteria