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Molecular design of dual inhibitors of PI3K and potential molecular target of cancer for its treatment: A review

Yuanze Wang, Micky D. Tortorella

2021European Journal of Medicinal Chemistry39 citationsDOIOpen Access PDF

Topics & Concepts

PI3K/AKT/mTOR pathwayHistone deacetylaseChemistryKinaseAcetylationDiscovery and development of mTOR inhibitorsComputational biologyCancer researchSignal transductionPharmacologyHistoneBiologyBiochemistryGeneHistone Deacetylase Inhibitors ResearchPI3K/AKT/mTOR signaling in cancerProtein Degradation and Inhibitors
Molecular design of dual inhibitors of PI3K and potential molecular target of cancer for its treatment: A review | Litcius