Rosemary oil low energy nanoemulsion: optimization, µrheology, <i>in silico, in vitro, and ex vivo</i> characterization
Nupur Vasdev, Mayank Handa, Prashant Kesharwani, Rahul Shukla
Abstract
permeation studies showed more drug penetration from the nanoemulsion as compared to the plain drug. The prepared nanoemulsion was found to be stable for 3 months at 4, 25, and 45 °C of storage. This low energy preparation method can be advantageous for the preparation of scalable nanoemulsion and can be a futuristic therapeutic for Alzheimer's disease.
Topics & Concepts
PermeationZeta potentialChemistryAcetylcholinesteraseDonepezilChromatographyIsopropyl myristateEx vivoPulmonary surfactantIn vitroMaterials scienceNanoparticleBiochemistryNanotechnologyEnzymeMedicineMembranePathologyDementiaDiseaseAdvancements in Transdermal Drug DeliveryProteins in Food SystemsAdvanced Drug Delivery Systems