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Anticancer Potential of Lichens’ Secondary Metabolites

Zuzana Solárová, Alena Líšková, Marek Samec, Peter Kubatka, Dietrich Büsselberg, Peter Solár

2020Biomolecules153 citationsDOIOpen Access PDF

Abstract

Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and anticancer. Although no clinical study has been conducted yet, there are number of in vitro and in vivo studies demonstrating anticancer effects of lichen metabolites. The main goal of our work was to review most recent published papers dealing with anticancer activities of secondary metabolites of lichens and point out to their perspective clinical use in cancer management.

Topics & Concepts

LichenAntifungalAnthraquinonesIn vivoPharmacologyChemistryBiologyComputational biologyMicrobiologyBiotechnologyBotanyLichen and fungal ecologyBryophyte Studies and RecordsMicrobial Natural Products and Biosynthesis
Anticancer Potential of Lichens’ Secondary Metabolites | Litcius